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$38,990
PALA2086364 MLS
Prime commercial lease opportunity on Columbia Avenue with strong traffic counts and exceptional exposure along one of Lancaster’s busiest corridors, with 13,000+ vehicles per day. Situated on 0.19 acres, this property combines high visibility with 15 on-site parking spaces, a rare and meaningful asset for businesses that need both exposure and customer convenience. The existing 2,795 square feet of improvements are located within the R4 zoning district and may accommodate office, retail, service, and other qualifying business uses, including potential suitability for permitted corner-location commercial occupancy, subject to zoning approval. Flexible suite options from 675 to 2,795 square feet and competitive lease pricing make this a strong fit for a variety of commercial users. Contact listing agent for lease terms and availability.

843 Columbia Ave, Lancaster

Listing courtesy of RE/MAX SmartHub Realty. Contact: (717) 208-4444
$50,551
PALA2086184 MLS
Highly visible commercial property in Ephrata Borough with exposure to approximately 14,000–18,000 vehicles per day along a well-established corridor near downtown amenities and major community anchors including Dairy Queen, Ephrata Recreation Center, and Cloister Shopping Center. Excellent signage possible! The location offers immediate access to Routes 272 and 322 and is just 7 miles from the Pennsylvania Turnpike. The building contains approximately 5,030 gross square feet, including approximately 3,121 square feet of office space on the upper floors and 1,909 square feet of contractor or storage space on the lower level. The office area is accessed from the rear upper parking lot and deck, while the lower level has a separate front exterior entrance and internal stair connection. The property also features 25 parking spaces, mature landscaping, a large lot, and a spacious deck for outdoor seating. Zoned Highway Commercial. Landlord open to tenant improvements. Base rent is $10.05/SF plus $2.95/SF NNN, totaling $5,449/month. Tenant pays electric, gas, water, sewer, trash, HVAC maintenance/repairs/replacement, landscaping, snow removal, and liability insurance.

722 W Main St, Ephrata

Listing courtesy of PPM Real Estate, Inc.. Contact: 7173943374
$120,557
PALA2086056 MLS
Discover an exceptional opportunity to sublease +/-6,043 SF of beautifully finished office space in the heart of Lancaster City. This versatile workspace features private offices, conference rooms, cubicle areas, restrooms, and a kitchenette, making it ideal for businesses of all sizes. Enjoy excellent visibility directly across from the Lancaster County Convention Center and take advantage of the close proximity to popular city attractions. This prime location offers both convenience and a vibrant atmosphere, perfect for fostering productivity and collaboration. Lease rate: $19.95/SF Modified Gross (tenants pay electric, janitorial, gas, voice & data). Don’t miss out on this fantastic opportunity!

29 E King St Unit #SUITE 101, Lancaster

Listing courtesy of Compass Real Estate, LLC. Contact: (717) 431-8300
$950
PALA2085940 MLS
High traffic commercial space available in great location! On the corner of Rt. 897 and 272 in Denver, caddy corner from Weaver Markets. Space consists of two separate rooms with brand new flooring and paint. Ample parking on East side of building accessible from Rt. 272. Shared lunch room and bathroom. Large parking area access from Rt. 272. Approximately 1,600 sq. ft. Additional 1,600 sq. ft. of space is available.

2651 N Reading Rd Unit #B, Denver

Listing courtesy of Horning Farm Agency Inc. Contact: 6102865183
$1,150
PALA2085930 MLS
High traffic commercial space available in great location! On the corner of Rt. 897 and 272 in Denver, caddy corner from Weaver Markets. Space consists of large seating area/office space perfect for cafe area for coffee shop, separate private office room with historic building's built-in shelving. Shared lunch room and bathroom. Brand new interior. Approx. 1,600 sq. ft. Large parking area access of Rt. 272. Additional 1,600 sq. ft. of space available.

2651 N Reading Rd Unit #A, Denver

Listing courtesy of Horning Farm Agency Inc. Contact: 6102865183
$2,435
PALA2085960 MLS ⋅ Ephrata Business Center BLDG.
3rd Floor - 5,843 sq ft - Possible uses include office, showroom, warehouse, classroom, etc. - 6' to 7' ceiling - Sprinklered - 2 powder rooms - Owner would consider mini splits for heating and a/c - Elec costs will be added to the rent, currently 362/month

400 W Main St, Ephrata

Listing courtesy of Kingsway Realty - Ephrata. Contact: (717) 733-4777
$8,223
PALA2085944 MLS ⋅ Ephrata Business Center BLDG.
The former Nolt's Office Furniture - 14,097 sq. ft. 1st floor - 5 rooms office/retail space - 2 powder rooms - 1 dedicated 8x8 tailgate dock - Private office - 3 large sales/display rooms, lunch room, shop - 6'8" to 7' ceilings - Wall to wall carpet in sales rooms - 1 year minimum lease term - See document for electric fees

400 W Main St, Ephrata

Listing courtesy of Kingsway Realty - Ephrata. Contact: (717) 733-4777
$30,720
PALA2084392 MLS
This 1320 sf with a 352 sf mezzanine walk up retail shop is perfectly located next to supporting retail and businesses on the zeroth block of Queen St. THE OWNERSHIP WANTS AN ICE CREAM BUSINESS TO SUPPORT THE OTHER DESTINATION ENTERTAINMENT BUSINESS ALREAY ON THE BLOCK AND WILL ASSIST IN FINANCING BUILD OUT.

47 N Queen St N, Lancaster

Listing courtesy of Meedcor Realty. Contact: (717) 394-9500
$20
PALA2085404 MLS
Professional conference room available for rent – ideal for meetings, interviews, or small group work. Seats up to 6 with ergonomic office chairs. Includes high-speed Wi-Fi, whiteboard, ample power outlets, kitchen amenities, restrooms, and coffee/water are available for you and your clients. Flexible booking at $20/hr. Convenient location with a comfortable, professional atmosphere.

1656 W Main St, Ephrata

Listing courtesy of Astoria Realty Advisors LLC. Contact: 7174256264
$25
PALA2085412 MLS
Spacious Event & Meeting Venue – Seats Up to 100 Now available – a versatile event and meeting space ideal for business gatherings, trainings, workshops, banquets, and community events. This well-appointed venue accommodates up to 100 guests and offers flexible booking options starting at just $25/hour. Features & Amenities: High-speed Wi-Fi for presentations, streaming, and remote participation. Multiple power outlets throughout for easy device setup Folding tables & chairs for customizable layouts Kitchen amenities for food prep and storage On-site restrooms for guest convenience Coffee and water available for refreshments Centrally located with easy access and ample space, this venue offers the comfort, flexibility, and amenities you need to host a successful event. Schedule your tour today and secure your date!

1656 W Main St, Ephrata

Listing courtesy of Astoria Realty Advisors LLC. Contact: 7174256264
$9,776
PALA2085174 MLS
Well-maintained ±940 SF second-floor office suite located just off the Route 30 / Centerville Road exit in East Hempfield Township. Situated within a professional business park, the suite offers 4–5 spacious private offices, an open work area, and an IT/storage room, providing a functional layout for a variety of professional users. Abundant natural light throughout enhances the workspace, while shared amenities include a breakroom, restrooms, and a common lobby with directory signage. Additional features include monument signage along Hempland Road and access to a shared on-site parking lot. Base rent is $10.40/SF with 2026 NNN estimated at $3.72/SF, totaling $1,106.07 per month.

3004 Hempland Rd Unit #SECOND FLOOR, Lancaster

Listing courtesy of PPM Real Estate, Inc.. Contact: 7173943374
$2,300
PALA2085166 MLS
COMMERICAL OFFICE SPACE AVAILABLE! Right along Route 322 in Ephrata (Lincoln Area), you'll find this spacious office building. Fresh paint and new flooring throughout. It offers a large reception area, a big open room that could be a conference area or a space to set up cubicles, several private offices and a new kitchenette. Lots of storage closets and built-ins throughout, 2 powder rooms, 7 parking spaces included, electric heat pump and cool central air. Any usage and signage must be approved through Ephrata Borough. Convenient location with great visibility!

1413 W Main St, Ephrata

Listing courtesy of Hauenstein Agency, Inc.. Contact: 7177339194
$136,931
PALA2085152 MLS
Sublease a premier office suite at 802 New Holland Ave, Suite 200, offering approximately 13,762 SF, primarily on the 2nd floor with an additional 1,800 SF on the 1st floor, featuring contemporary design, abundant natural light, and flexible layouts ideal for a professional office environment. Conveniently located on the northeast edge of Lancaster City adjacent to Grandview Plaza and between the Rossmere and Grandview Heights neighborhoods, the property is about 1 mile from Route 30, downtown Lancaster, and the Lancaster Amtrak Station, with extensive nearby amenities and medical neighbors that enhance daily convenience for staff and clients. Lease Rate: $9.95/SF MODIFIED GROSS!

802 New Holland Ave Unit #200, Lancaster

Listing courtesy of Compass Real Estate, LLC. Contact: (717) 431-8300
$23,040
PALA2085102 MLS
Suite #1 at 1689 Crown Ave offers ±1,440 SF of professional office space in Ridgeview Executive Park, conveniently located just off Route 30 and Oregon Pike. Space features direct, glass entry into a welcoming reception area, four private offices, a conference room, and a break room with kitchenette. Large windows provide abundant natural light throughout the space. Shared restrooms and ample parking are available in the unreserved, shared lot. $16.00/SF Modified Gross ($1,920/month). Tenant pays phone, internet, suite janitorial, and 30% pro-rata share of monthly electric.

1689 Crown Ave Unit #1, Lancaster

Listing courtesy of PPM Real Estate, Inc.. Contact: 7173943374
$25,800
PALA2084610 MLS
Rare opportunity to lease a stunning mixed-use commercial space in the heart of Lancaster at the Slaymaker Building. This expansive loft-style suite features beautiful exposed beams, soaring ceilings, and large windows that flood the space with natural light, creating a bright and inspiring work environment. The open floor plan offers incredible flexibility for a variety of uses, including creative offices, studio space, showroom, wellness services, or collaborative workspaces. Gorgeous hardwood floors throughout complement the building's industrial character while maintaining a warm, professional atmosphere. The layout includes a large open office area with a private rooms suitable for an office or meeting space, a restroom, a utility room, and a welcoming foyer entry. The spacious main area provides ample room for workstations, creative production, or client-facing operations. Located in a vibrant area with convenient access to downtown amenities, this unique commercial space blends historic character with modern functionality—ideal for businesses seeking a distinctive and flexible workspace. Schedule your private showing today to see the potential this space offers!

117 S West End Ave, Lancaster

Listing courtesy of Cavalry Realty LLC. Contact: (717) 932-2599
$2,000
PALA2084968 MLS
Prime Commercial Space for Lease – Excellent Visibility in Ephrata! Looking for the perfect spot to grow your business? This 2,850 sq. ft. commercial space offers incredible visibility on a busy Ephrata highway—ideal for attracting customers and clients alike. The layout provides flexible options to suit a variety of business types, whether you’re opening a professional office, accounting firm, or modern salon. This space features public water and sewer, and gas heat. A convenient on-site parking lot ensures easy access for both staff and customers. The building’s location offers steady traffic flow and outstanding exposure, making it a standout choice for businesses seeking a strong local presence. Offered at $2,000/month, this property delivers exceptional value for the size, location, and potential it offers. Don’t miss this opportunity to establish your business in one of Ephrata’s most visible and accessible commercial corridors!

325 S Reading Rd, Ephrata

Listing courtesy of Berkshire Hathaway HomeServices Homesale Realty. Contact: 8003833535
$578,135
PALA2084532 MLS
Multifunctional clean industrial distribution space with nice office. 70,077 SF for lease in Greenfield Corporate Center. Sprinklers, full HVAC in office, gas unit heaters in warehouse. 480V 1200 Amps. 1 drive in door, 5 docks. 20' clear ceilings. $8.25NNN. On site private parking.

1828 Freedom Road Unit #101, Lancaster

Listing courtesy of High Associates Ltd.. Contact: (717) 293-4477
$10,000
PALA2084502 MLS
918 SF of well-maintained retail/office space available in a professional complex in Leola. The suite features a functional layout suitable for a wide variety of business types. The complex is home to a mix of established tenants including medical, financial and service-based professionals, creating a strong business environment. Conveniently located along a well-traveled corridor with easy access to surrounding communities and amenities, this space provides a flexible, affordable option for professional users seeking a prime Lancaster County location.

351 W. Main St, Leola

Listing courtesy of Bennett Williams Realty, Inc.. Contact: 7178435555
$19,012
PALA2084416 MLS
Position your business in the heart of New Holland with this versatile, high-visibility office suite located directly next to Sheetz. Offering 1,950 square feet of functional space, this layout is perfectly suited for professional services, medical practitioners, or creative agencies. Key Features include Professional Entry: A welcoming waiting area featuring a built-in check-in counter ensures a polished first impression for your clients. Versatile Layout: Includes 5 to 6 private offices—ideal for executive suites or medical exam rooms, complemented by a spacious open area for cubicles, collaborative workstations, or a large conference setup. Flexible Availability: Currently occupied, but available for your team with just 30 days' notice. Ideal For: Marketing firms, financial or investment groups, lenders, or medical users requiring a mix of private and common areas.

684 W Main St, New Holland

Listing courtesy of High Associates Ltd.. Contact: (717) 293-4477
$45,880
PALA2084340 MLS
Introducing 312 Honeysuckle Dr in Marietta, PA – an exceptional lease opportunity for your business. This 2,480 SF unit, currently leased to Drayer Physical Therapy offers an open floor plan with professional finishes and a nice layout. Embrace the potential of this prominent location to elevate your business to new heights at 312 Honeysuckle Dr. Lease Rate: $18.50/SF NNN

312 Honeysuckle Dr, Marietta

Listing courtesy of Compass Real Estate, LLC. Contact: (717) 431-8300
$170,449
PALA2084134 MLS
1695 State Street, East Petersburg offers Suite 2 with a total of 21,006 SF, or it can be demised into Suite 2A (12,035 SF) or Suite 2B (8,971 SF), with the full space available at $14/SF NNN and the smaller suites at $19/SF modified gross; the premises feature a modern, recently renovated, professionally designed layout with a predominantly open plan, private offices, conference rooms, multiple kitchenettes and coffee stations, bright interiors, and a full-building backup generator, all in a prime East Petersburg location with excellent visibility, convenient access to major roadways, a strong surrounding business community, and over 500 surface parking spaces.

1695 State St Unit #SUITE 2B, East Petersburg

Listing courtesy of Compass Real Estate, LLC. Contact: (717) 431-8300
$294,084
PALA2084128 MLS
1695 State Street, East Petersburg offers Suite 2 with a total of 21,006 SF, or it can be demised into Suite 2A (12,035 SF) or Suite 2B (8,971 SF), with the full space available at $14/SF NNN and the smaller suites at $19/SF modified gross; the premises feature a modern, recently renovated, professionally designed layout with a predominantly open plan, private offices, conference rooms, multiple kitchenettes and coffee stations, bright interiors, and a full-building backup generator, all in a prime East Petersburg location with excellent visibility, convenient access to major roadways, a strong surrounding business community, and over 500 surface parking spaces.

1695 State St Unit #SUITE 2, East Petersburg

Listing courtesy of Compass Real Estate, LLC. Contact: (717) 431-8300
$228,665
PALA2084132 MLS
1695 State Street, East Petersburg offers Suite 2 with a total of 21,006 SF, or it can be demised into Suite 2A (12,035 SF) or Suite 2B (8,971 SF), with the full space available at $14/SF NNN and the smaller suites at $19/SF modified gross; the premises feature a modern, recently renovated, professionally designed layout with a predominantly open plan, private offices, conference rooms, multiple kitchenettes and coffee stations, bright interiors, and a full-building backup generator, all in a prime East Petersburg location with excellent visibility, convenient access to major roadways, a strong surrounding business community, and over 500 surface parking spaces.

1695 State St Unit #SUITE 2A, East Petersburg

Listing courtesy of Compass Real Estate, LLC. Contact: (717) 431-8300
$83,754
PALA2083940 MLS
Fantastic mechanical contractor location with air-conditioned showroom space, office/conference and great production/storage spaces with dock. $11.00NNN per square foot per year. Parking at the building. Convenient location 1 block off Columbia Avenue. A Retail/Industrial flex combo that is hard to find. Please contact Agent for tour with 24 hours minimum notice. Daytime weekdays only. Business is open and in full operation, please do not visit without appointment. No sign is present. Tenant to confirm future Use with West Hempfield Twp.

602 S 16th St, Columbia

Listing courtesy of High Associates Ltd.. Contact: (717) 293-4477
$35,000
PALA2083916 MLS
This stand-alone office building is perfectly located for a combination of Lancaster and Lititz accessibility is ideal for businesses seeking privacy and a productive workspace. Key Features: a private ground floor entrance, abundant natural light throughout the building, large perimeter offices with windows, bullpen area, and ample parking on-site for employees and clients. Owner is willing to work with prospective tenants on improvements and changes. Also available as 5,000 SF full floor – see MLS# PALA2057860.

118 W Airport Rd, Lititz

Listing courtesy of Mountain Realty ERA Powered. Contact: (717) 390-8701
$3,000
PALA2083456 MLS
Second Floor office in convenient location on East Main Street (Route 23), Rent includes all utilities.

342 E Main St Unit #SUITE 211, Leola

Listing courtesy of U.S. Commercial Realty. Contact: (717) 735-6000
$6,900
PALA2083452 MLS
Second Floor corner office in convenient location on East Main Street (Route 23), Rent includes all utilities.

342 E Main St Unit #SUITE 202, Leola

Listing courtesy of U.S. Commercial Realty. Contact: (717) 735-6000
$6,360
PALA2083454 MLS
Second Floor office in convenient location on East Main Street (Route 23), Rent includes all utilities.

342 E Main St Unit #SUITE 204, Leola

Listing courtesy of U.S. Commercial Realty. Contact: (717) 735-6000
$45,500
PALA2083450 MLS
First-floor executive suite in a beautifully renovated office building on East Main Street (Route 23). Includes a lobby/recaption area, conference room, four (4) private offices and a kitchenette/file room.

342 E Main St Unit #SUITE 100, Leola

Listing courtesy of U.S. Commercial Realty. Contact: (717) 735-6000
$29,748
PALA2083462 MLS
Professional office suite in high visibility location on East Main Street (PA Route 23). Offers private offices, conference room and kitchenette.

352 E Main St Unit #SUITE 200, Leola

Listing courtesy of U.S. Commercial Realty. Contact: (717) 735-6000